생화학분자생물학회

	Yang-Sook Chun ( chunys@snu.ac.kr )
	2011-present	Full Professor, Department of Physioloy, Seoul University, South Korea
	2017-2018	Visiting Scholar, Department of Engineering, Yokohama National University, Japan
	2006-2011	Associate Professor, Department of Physioloy, Seoul University, South Korea
	2002-2006	Assistant Professor, Department of Physioloy, Seoul University, South Korea
	2000-2002	BK Assistant Professor, Brain Korea, College of Medicine, Seoul National University, South Korea
	2002-2006	PhD, College of Pharmacy& College of Medicine, Department of Pharmacology, Seoul National University, South Korea
	1997-1998	Post-doctoral fellow, Hematology & Oncology, Harvard Medical School BWH, USA
	1996–1997	Post-doctoral fellow, Department of Pathology, Harvard Medical School MGH, USA
	1992–1994	Post-doctoral fellow, Department of Carcinogenesis, National Cancer Center, Japan
	1984-1986	MS, College of Pharmacy, Seoul National University, South Korea

Neddylation steers the fate of cellular receptors

Cellular receptors regulate physiological responses by interacting with ligands, thus playing a crucial role in intercellular communication. Receptors are categorized on the basis of their location and engage in diverse biochemical mechanisms, which include posttranslational modifications (PTMs). Considering the broad impact and diversity of PTMs on cellular functions, we focus narrowly on neddylation, a modification closely resembling ubiquitination. We systematically organize its canonical and noncanonical roles in modulating proteins associated with cellular receptors with the goal of providing a more detailed perspective on the intricacies of both intracellular and cell-surface receptors.

Exp Mol Med. 2024 Dec;56(12):2569-2577. doi: 10.1038/s12276-024-01358-0.
https://pubmed.ncbi.nlm.nih.gov/39623094/