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Autonomic control of energy balance and glucose homeostasis

  • 작성자

    Jong-Woo Sohn
  • 작성일자

    2022-07-19
  • 조회수

    56
Jong-Woo Sohn( jwsohn@kaist.ac.kr )
2014-presentAssistant & Associate Professor, Department of Biological Sciences, KAIST, Daejeon, South Korea
2009-2014Postdoctoral Researcher, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA
2008-2009Postdoctoral Fellow, BK21 Research Division of Human Life Science, Seoul National University, Seoul, South Korea
2003-2008Teaching Assistant, Department of Physiology, Seoul National University College of Medicine, Seoul, South Korea
2003-2008PhD, Department of Physiology, Seoul National University College of Medicine, Seoul, South Korea
1997-2003MD, Seoul National University College of Medicine, Seoul, South Korea

Autonomic control of energy balance and glucose homeostasis

Neurons in the central nervous system (CNS) communicate with peripheral organs largely via the autonomic nervous system (ANS). Through such communications, the sympathetic and parasympathetic efferent divisions of the ANS may affect thermogenesis and blood glucose levels. In contrast, peripheral organs send feedback to the CNS via hormones and autonomic afferent nerves. These humoral and neural feedbacks, as well as neural commands from higher brain centers directly or indirectly shape the metabolic function of autonomic neurons. Notably, recent developments in mouse genetics have enabled more detailed studies of ANS neurons and circuits, which have helped elucidate autonomic control of metabolism. Here, we will summarize the functional organization of the ANS and discuss recent updates on the roles of neural and humoral factors in the regulation of energy balance and glucose homeostasis by the ANS.

Exp Mol Med. 2022 Apr;54(4):370-376. doi: 10.1038/s12276-021-00705-9.
https://pubmed.ncbi.nlm.nih.gov/35474336/