간행물

생화학분자생물학회입니다.


BmB Reports

A novel role of Hippo-Yap/TAZ signaling pathway in lymphatic vascular development

  • 작성자

    Boksik Cha
  • 작성일자

    2021-03-22
  • 조회수

    1
Name: Boksik, Cha ( boksik-cha@dgmif.re.kr )
2019-present Senior Researcher, New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF), Daegu City, Korea
2017-2019 2017-2019 Research Assistant Member, Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, OK, USA
20013-2017 Postdoctoral research fellow, Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, OK, USA
2008-2013 Ph.D., Department of Life Science, University of Seoul, Seoul, Korea

A novel role of Hippo-Yap/TAZ signaling pathway in lymphatic vascular development

The lymphatic vasculature plays important roles in regulating fluid homeostasis, intestinal lipid absorption, and immune surveillance. Malfunction of lymphatic vasculature leads to several human diseases. Understanding the fundamental mechanism in lymphatic vascular development could provide a new therapeutic approach. Hippo-YAP/TAZ signaling pathway has emerged as a key player in controlling organ size and tissue homeostasis. Here, we review the molecular mechanisms by which Hippo-YAP/TAZ pathway regulating lymphatic specification, sprouting, and maturation.


https://pubmed.ncbi.nlm.nih.gov/33691907/
BMB Rep. 2021 Mar 11;5301. Online ahead of print.