생화학분자생물학회입니다.
Autonomic control of energy balance and glucose homeostasis
작성자
Jong-Woo Sohn작성일자
2022-07-19조회수
57Jong-Woo Sohn( jwsohn@kaist.ac.kr ) | ||
2014-present | Assistant & Associate Professor, Department of Biological Sciences, KAIST, Daejeon, South Korea | |
2009-2014 | Postdoctoral Researcher, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA | |
2008-2009 | Postdoctoral Fellow, BK21 Research Division of Human Life Science, Seoul National University, Seoul, South Korea | |
2003-2008 | Teaching Assistant, Department of Physiology, Seoul National University College of Medicine, Seoul, South Korea | |
2003-2008 | PhD, Department of Physiology, Seoul National University College of Medicine, Seoul, South Korea | |
1997-2003 | MD, Seoul National University College of Medicine, Seoul, South Korea |
Autonomic control of energy balance and glucose homeostasis
Neurons in the central nervous system (CNS) communicate with peripheral organs largely via the autonomic nervous system (ANS). Through such communications, the sympathetic and parasympathetic efferent divisions of the ANS may affect thermogenesis and blood glucose levels. In contrast, peripheral organs send feedback to the CNS via hormones and autonomic afferent nerves. These humoral and neural feedbacks, as well as neural commands from higher brain centers directly or indirectly shape the metabolic function of autonomic neurons. Notably, recent developments in mouse genetics have enabled more detailed studies of ANS neurons and circuits, which have helped elucidate autonomic control of metabolism. Here, we will summarize the functional organization of the ANS and discuss recent updates on the roles of neural and humoral factors in the regulation of energy balance and glucose homeostasis by the ANS.
Exp Mol Med. 2022 Apr;54(4):370-376. doi: 10.1038/s12276-021-00705-9.
https://pubmed.ncbi.nlm.nih.gov/35474336/