생화학분자생물학회

	Name: Won Ho Yang ( bionicwono@yonsei.ac.kr )
	2019-present	Assistant Professor, Department of Systems Biology, Yonsei University
	2016-2019	Scientific Associate, SBP Discovery Institute / UC Santa Barbara
	2009-2016	Senior Postdoctoral Associate, SBP Discovery Institute / UC Santa Barbara
	2008-2009	Postdoctoral Associate, HHMI / UC San Diego
	2003-2007	Ph.D., Department of Biology, Yonsei University

Remodeling of host glycoproteins during bacterial infection

Protein glycosylation is a common post-translational modification found in all living organisms and the modification in bacterial pathogens has a pivotal role in their infectious processes including pathogenicity, immune evasion, and host-pathogen interactions. Importantly, many key proteins of host immune systems are also glycosylated and bacterial pathogens notably modulate glycosylation on these host proteins to facilitate pathogenesis through the induction of abnormal host protein activity and abundance. In recent years, there is an increased interest in studying the regulation of host protein glycosylation caused by bacterial pathogens to fully understand bacterial pathogenesis. In this review, we focus on how bacterial pathogens regulate remodeling of host glycoproteins during infections to promote the pathogenesis.


BMB Rep. 2021 Oct 22;5459. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/34674797/