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BMB Reports

Integrative understanding of immune-metabolic interaction

  • 작성자

    Jun Young Hong
  • 작성일자

    2022-07-19
  • 조회수

    74
Name: Jun Young Hong ( junyoung.hong@yonsei.ac.kr )
2021-presentProfessor, Department of Systems Biology, Yonsei University, South Korea
2015-2021Postdoctoral Fellow, Department of Immunobiology, Yale University, USA
2010-2015PH.D., Department of Molecular and Integrative Physiology, University of Michigan in Ann Arbor, USA

Integrative understanding of immune-metabolic interaction

Recent studies have revealed that the immune system plays a critical role in various physiological processes beyond its classical pathogen control activity. Even under a sterile condition, various cells and tissues can utilize the immune system to meet a specific demand for proper physiological functions. Particularly, a strong link between immunity and metabolism has been identified. Studies have identified the reciprocal regulation between these two systems. For example, immune signals can regulate metabolism, and metabolism (cellular or systemic) can regulate immunity. In this review, we will summarize recent findings on this reciprocal regulation between immunity and metabolism, and discuss potential biological rules behind this interaction with integrative perspectives.


BMB Rep. 2022 Jun 2;5619. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/35651325/