생화학분자생물학회

	Name: Min Ju Shon ( mjshon@postech.ac.kr )
	2020-present	Assistant (2020-2024) and Associate Professor (2024-present), Dept. of Physics and School of I-BIO, POSTECH
	2017-2020	Postdoctoral Fellow (2017-2019) and Research Assistant Professor (2019-2020), Seoul National University
	2014-2016	Postdoctoral Associate, KAIST
	2008-2014	Ph.D., Dept. of Chemistry and Chemical Biology, Harvard University
	2007	B.S., Dept. of Chemistry, Seoul National University
	Name: Jaehyeon Shin ( jhyeonshin@postech.ac.kr )
	2023-present	MS-Ph.D. Integrated Program, Dept. of Physics, POSTECH
	2023	B.S., Dept. of Physics, POSTECH

Advancing Membrane Biology: Single-Molecule Approaches Meet Model Membrane Systems

Model membrane systems are powerful tools that enable focused studies of specific membrane components in simplified environments, free from the complexity of cellular membranes. To fully harness the potential of these systems, integration with single-molecule techniques is essential. However, the structural and dynamic properties of model membranes have historically posed challenges for such integration. This mini-review explores the evolution of model membrane systems as they have adapted to incorporate single-molecule techniques. It highlights key innovations and modifications that have facilitated this synergy, covering various model membrane platforms such as free-standing lipid bilayers and liposome systems, and their integration with methods like electrophysiology, force spectroscopy, and fluorescence microscopy. By examining these advancements, the review provides insights into current research trends in model membrane studies and identifies areas for future improvement. This resource is intended for researchers looking to leverage the combined power of model membranes and single-molecule techniques in their exploration of membrane-mediated cellular processes.


BMB Rep. 2024 Dec 20. pii: 6384. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.gov/39701026/